Treatment Possibilities of Muscle Cramps in Patients with Liver Cirrhosis

Abstract Muscle cramps appearing in liver cirrhosis substantially affect the quality of life these patients. The prevalence painful muscle can be up to 88%. exact mechanism by which occur is unknown. management this symptom not easy because there no uniformly accepted recommendation about what kind supplementation or medicine (or both) used exactly. aim our study review treatment options for cirrhosis. We found literature (using keywords „liver cirrhosis", „muscle cramps", „treatment" and „quality life") 32 articles topic. Treatment currently are: vitamin supplementations (vitamin E, 1 - α hydroxy D), amino acid (taurine, branched chain acids, L carnitine, albumin), mixed herbal medicines (Niuche-Shen-Qui-Wan), zinc medications (eperisone hydrochloride, quinine quinidine sulphate, baclofen, methocarbamol, orphenadrine). Vitamin are targeting possible pathophysiological causes (nerve function energy metabolism alterations unique cirrhosis). New aspects started use especially antispasmodic agents (methocarbamol, orphenadrine) antispasticity (baclofen) relieve cramps. also a multicenter two systematic reviews (performed 2013 2014). From 2014 article appeared topic we considered it important survey new next already known.